Calibre is insytalled but does not work anymore

[regislnd]

Hello the community, happy to join,
I am under Windows 11, I installed Calibre like 10 days ago, all worked well, i could get the ebooks loaded on it, tranfered to my Kindle parperwhite. Life was great.
But since 2 days, i cannot launch it anymore. I looked at all my Windows defender details, I have an Orange protection suite too on the PC with my mobile contract, but as far as i cant see, nothing seems to lock the application so I missed something.
i look into other users case, they tried also via the Calibre portbale app, i did it, but did not solve anything. Any Good idea?
By the way, be kind in your response as I am not a professional of computer science so to use simple vocabulary will help and my English command is far from perfection too ;-).
Enjoy the day
Regis